Germline Ablation

Species: Nematode (Taxid: 6239)
Factor:
Manipulation:
Effect:

Germline ablation increases mean and maximum lifespan by 85% and 113% [Wollam et al., 2012].

In hermaphrodite C. elegans, removing sperm and egg-producing cells extends lifespan by 50% [23239738].

Mean: +85
Maximum: +113

References:
  • 23239738: A steroid receptor-microRNA switch regulates life span in response to signals from the gonad.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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