Denigma

spg-7 RNAi

Species: Nematode (Taxid: 6239)
Factor: spg-7
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

Kockdown of spg-7 via RNAi started after the animal reached the late L4 stage has no significant effect on mean lifespan [22103665]. RNA interference of spg-7 in adulthood results in a 23% increase in mean lifespan [17411345].

Mean: 0 to +23

References:
  • 22103665: Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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