Denigma

rpa-0 RNAi

Species: Nematode (Taxid: 6239)
Factor:
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

Knockdown of rpa-0 via RNAi started after the animal reached the late L4 stage increases mean and maximum lifespan by 7-11% and 11%, respectively [22103665].

Mean: +7 to +11
Maximum: +11

References:
  • 22103665: Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan.


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