Denigma

eft-2 RNAi

Species: Nematode (Taxid: 6239)
Factor: eft-2
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

Post-developmental RNA interference reduces mean lifespan by 15% [17673661]. Knockdown of eft-2 started after the animal reached the late L4 stage increases mean and maximum lifespan by 6-27% and 8%, respectively [22103665].

Mean: -15 to +27
Maximum: +8

References:
  • 22103665: Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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