Denigma

K01C8.7 RNAi

Species: Nematode (Taxid: 6239)
Factor: K01C8.7
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

K01C8.7 RNAi increases mean and maximum lifespan by 20% and 21%, respectively. Lifespan extension by RNAi of K01C8.7 is not suppressed by daf-16. K01C8.7 RNAi animals have lower ATP content and oxygen consumption [12447374].

Mean: +20
Maximum: +21

References:
  • 12447374: A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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