Denigma

cchl-1 RNAi

Species: Nematode (Taxid: 6239)
Factor: cchl-1
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

cchl-1 RNAi extends mean and maximum lifespan by 55% and 57%, respectively. Lifespan extension by RNAi of cchl-1 is not suppressed by daf-16 [12447374].

cchl-1 RNAi animals have lower ATP content and oxygen consumption [12447374].

Mean: +55
Maximum: +57

References:
  • 12447374: A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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