Denigma

F26E4.6 RNAi

Species: Nematode (Taxid: 6239)
Factor: F26E4.6
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

F26E4.6 RNA interference extends mean and maximum lifespan by about 48% and 50%, respectively. Lifespan extension by F26E4.6 RNAi is not suppressed by daf-16. F26E4.6 RNAi animals have lower ATP content and oxygen consumption [12447374].

Mean: +48
Maximum: +50

References:
  • 12447374: A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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