Denigma

CG3776 overexpression

Species: Fruit fly (Taxid: 7227)
Factor: CG3776
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of CG3776 (alias Jhebp29) reduces the mean lifespan, where the reduction in males is slightly higher.

The lifespan of female and male flies with overexpressed CG3776 is reduced by 35% and 42.6%, respectively when compared with Oregon R flies [18275960].

Mean: -35 to -42.6

References:
  • 18275960: Overexpression of Drosophila juvenile hormone esterase binding protein results in anti-JH effects and reduced pheromone abundance.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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