Denigma

Aut1 RNAi

Species: Fruit fly (Taxid: 7227)
Factor: Aut1
Manipulation: Loss-of-Function, Knockout, RNA Interference
Effect:

Aut1 depletion by RNAi form the first day of imaginal stage shortens lifespan by 28% on average in Drosophila and causes morphological behavioural features of premature aging [18219227].

Mean: -28

References:
  • 18219227: Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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