Denigma

sdhC dominant negative overexpression

Species: Fruit fly (Taxid: 7227)
Factor:
Manipulation: Loss-of-Function, Overexpression, Mutation
Effect:

Mutants expressing a dominant negative form of sdhC in the nervous system have a 22% reduced mean lifespan and signs of oxidative stress induction [17854771].

Mean: -22

References:
  • 17854771: A mev-1-like dominant-negative SdhC increases oxidative stress and reduces lifespan in Drosophila.


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