Denigma

Foxm1 overexpression

Species: House mouse (Taxid: 10090)
Factor: Foxm1
Manipulation: Gain-of-Function, Overexpression
Effect:

Increased hepatocyte expression in 12-month-old (aged) transgenic mice of Foxm1b alone is sufficient to restore hepatocyte proliferation to levels found in 2-month-old (young) regenerating liver [14647066].


References:
  • 14647066: Growth hormone stimulates proliferation of old-aged regenerating liver through forkhead box m1b.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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