Bub3 and Rae1 haploinsuficiency

Species: House mouse (Taxid: 10090)
Factor: Bub3
Manipulation:
Effect:

Haploinsufficiency of Bub3 and Rae1, but not haploinsufficiency of either gene by itself, reduces lifespan by 12% and appears to accelerate aging [16476774].

Mean: -12

References:
  • 16476774: Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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