Denigma

Tsc1 overexpression

Species: Fruit fly (Taxid: 7227)
Factor: Tsc1
Manipulation: Overexpression
Effect:

Ubiquitously overexpression of UAS constructs (via the daughterless (da)-GAL-4 driver) containing dTSC1 extends mean lifespan at 29°C by 14% [15186745].

Mean: +14

References:
  • 15186745: Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR
    • Comparisons:
  • da-GAL4/UAS-dTsc1 vs. +/da-GAL4 : 11.5(mean) 29.0(max) <0.0001(p-value)

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