Denigma

to overexpression

Species: Fruit fly (Taxid: 7227)
Factor: to
Manipulation: Gain-of-Function, Overexpression
Effect:

Overexpression of to adult neurons, pericerbral or abdonimal fat body increases male and female lifespan. to overexpression in the adult nervous system, head fat body and abdominal fat body results in 25, 20 and 12-18% increase of mean lifespan. on average the mean lifesapn is extended for males and females by 18 and 26%, while maximum lifespan of male and female is increased by 13 and 25% [20519778].

Mean: +12 to +26
Maximum: +13 to +25

References:
  • 20519778: Comparative transcriptional profiling identifies takeout as a gene that regulates life span.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Edit / Update (Admin) | Delete

    Comment on This Data Unit