Denigma

car mutation

Species: Fruit fly (Taxid: 7227)
Factor: car
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

Loss-of-function mutation in car results in reduction of mean lifespan by 34 - 63% and maximum lifespan by 28 - 29% [17435236].

Mean: -34 to -63
Maximum: -28 to -29

References:
  • 17435236: Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR
    • Comparisons:
  • carnation vs. Canton-S ( 25°C male ) : -62.8(mean) -29.4(max) <0.0001(p-value)
  • carnation vs. white1118 ( 29°C male ) : -33.7(mean) -27.6(max) <0.0001(p-value)

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