Denigma

pck-1 overexpression

Species: Nematode (Taxid: 6239)
Factor: pck-1
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

Overexpression of pck-1 greatly increases content of PEPCK-C, markedly induces enzyme activity and significantly increases mean, 75%ile, and maximum lifespan by 19-23%, 17-22%, and 21% [22810224].

Mean: +19 to +23
Maximum: +21

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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