Denigma

GCN5 deletion

Species: Budding yeast (Taxid: 4932)
Factor: GCN5
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Deletion of GCN5 decreases replicative lifespan of extension of rho+ and rho0 cells as well as suppresses lifespan extension by the retrograde response [15547318]. Deletion of GCN5 strongly reduces chronological lifespan [19801973].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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