NTH2 deletion

Species: Budding yeast (Taxid: 4932)
Factor: NTH2
Manipulation: Loss-of-Function, Knockout, Deletion
Effect:

Deletion of NTH2 shortens mean chronological lifespan by 39% (at 30 degree Celsus in BY4742) [22783207].

NTH2 mutant cells have elevated trehalose concentration before they enter the non-proliferative stationary growth phase which remained high during the stationary phase. NTH2 deletion cells have no altered ROS levels in pre-quiescent cells [22783207].

Mean: -39

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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