Denigma

Ilp5 mutation

Species: Fruit fly (Taxid: 7227)
Factor: Ilp5
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Abundance of Ilp5 mRNA is reduced under DR. Ilp5 null mutants have a normal lifespan under AL and a normal DR response. Ilp2 Ilp3 Ilp5 triple null mutants fail to have a normal response to DR. Their response is right shifted, with mutants being shorter-lived compared to wild-type on low but longer-lived on high yeast concentrations [20195512].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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