hif-1 mutation does not suppress lifespan extension of bDR or eat-2 mutation [19372390]. hif-1 deletion extends lifespan by 24%. hif-1 mutation extends lifespan under AL, but does not further extend lifespan extension under modified sDR. hif-1 mutation does not further extend rsks-1 lifespan. pha-4 RNAi slightly reduces lifespan in wild-type and hif-1 mutants, but hif-1 mutation extends lifespan of animals treated with control or pha-4 RNAi to a similar level [19461873].
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