HST2 overexpression

Species: Budding yeast (Taxid: 4932)
Factor: HST2
Manipulation: Gain-of-Function, Overexpression
Effect:

HST2 overexpression extends replicative lifespan. 0.5% glucose restriction does not increase lifespan of sir2;fob1;hst2 triple mutants [16051752]. DR increases lifespan of all four sir2;fob1;hstX(X = sirtuin) triple mutants [16741098; 17129213].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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