ATG16 deletion

Species: Budding yeast (Taxid: 4932)
Factor: ATG16
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

Under AL atg16 mutation shortens chronological, but not replicative lifespan. 0.5% glucose DR extends chronological lifespan of atg16 mutants, but amino-acid DR does not extend the short chronological lifespan of atg16 mutants (similar to several other autophagy mutants). ADE4 deletion in atg16 mutants results only in a partial extension of chronological lifespan by 0.5% glucose DR. The long chronological lifespan of tor1 mutants requires ATG16 [20421943].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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