pka1 deletion

Species: Fission yeast (Taxid: 4896)
Factor: pka1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

pka1 knockouts exhibits a three-fold increase in chronological lifespan with up to 187% longer maximum lifespan [16822282]. Deleting ser/thr cAMP-activated protein kinase pka1 extends chronological lifespan under normal condition, but there is no additive effect with DR [20075862].

Mean: +300
Maximum: +187

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR



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