Factors

We need to know every factor which determines lifespan.

Lifespan factors often but not always originate from defined genetic elements. They are not just genes, by definition they can be anything for which a Classifications schema can be build for that is related to the regulation of lifespan, such entities may include Single-Nucleotide Polymorphism, transcript variants, proteins and their complexes, compounds (i.e. small molecules like metabolites and drugs), etc. A factor should be based on a defined molecular entity or genomic position and been classified. It shall be highly flexible and scalable Concept.

While individual lifespan factors within each species or precise defined molecular entities will be captured within the Lifespan App, Data Entries of the Data App may summarize for instance the relevance of each factor class (e.g. homologous group; chemical derivate of related structure and properties, etc.) as well as draw overall conclusions. o

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  • Species: + -
  • symbol name observation species
    Intergenic Intergenic was found to be associated with longevity [21418511]. Intergenic was found to be associated with longevity [22533364]. Intergenic was found to be associated with longevity [14615589]. Intergenic was found to be associated with longevity [21782286]. Intergenic was found to be associated with longevity [22279548]. Human
    Intergenic (downstream of SSBP3 and MRPL37) Intergenic (downstream of SSBP3 and MRPL37) was found to be associated with longevity [21418511]. Human
    ND2 ND2 was found to be associated with longevity [10996007]. Human
    rs2495513 Human
    ATP8 ATP8 was found to be associated with longevity [10996007]. Human
    rs4291539 Human
    16S rRNA 16S rRNA was found to be associated with longevity [10996007]. Human
    rs10923806 Human
    APOE + TOMM40 APOE + TOMM40 was not found to be associated with longevity [21418511]. APOE + TOMM40 was not found to be associated with longevity [23040522]. Human
    rs1538287 Human
    ND2 ND2 was not found to be associated with longevity [12384792]. Human
    rs6540664 Human
    rs6701445 Human
    rs12088486 Human
    rs10514626 Human
    rs7583529 Human
    rs4505466 Human
    rs964403 Human
    rs3864051 Human
    rs712773 Human
    rs1562688 Human
    rs6769400 Human
    rs513154 Human
    rs571391 Human
    rs2670104 Human
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    • 25 of 724 factors
    Factors are an extension of GenAge and GenDR.

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