| PDE10A | phosphodiesterase 10A | SNPs near PDE10A were associated to longevity [22773346]. | Human |
| QKI | quaking homolog, KH domain RNA binding (mouse) | SNPs close to SQKI were associated with longevity [22773346]. | Human |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | XRCC5 was found to be associated with longevity [22406557; 16518718]. | Human |
| XDH | xanthine dehydrogenase | XDH was found to be associated with longevity [22406557; 22279548]. | Human |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | NTHL1 was found to be associated with longevity [22406557]. | Human |
| FOXO4 | forkhead box O4 | FOXO4 was found to be associated with longevity [21388494]. | Human |
| NTLH1 | nescient helix loop helix 1 | NTLH1 was found to be associated with longevity [22406557]. | Human |
| POLB | polymerase (DNA directed), beta | POLB was found to be associated with longevity [22406557]. | Human |
| RAD23B | RAD23 homolog B (S. cerevisiae) | RAD23B was found to be associated with longevity [22406557]. | Human |
| RAD52 | RAD52 homolog (S. cerevisiae) | RAD52 was found to be associated with longevity [22406557]. | Human |
| IGF2R | insulin-like growth factor 2 receptor | IGF2R was found to be associated with longevity [22406557]. | Human |
| GHSR | growth hormone secretagogue receptor | GHSR was found to be associated with longevity [22406557]. | Human |
| GHRHR | growth hormone releasing hormone receptor | GHRHR was found to be associated with longevity [22406557]. GHRHR was not found to be associated with longevity [19489743]. | Human |
| GSR | glutathione reductase | GSR was found to be associated with longevity [22406557]. | Human |
| ICAM1 | intercellular adhesion molecule 1 | ICAM1 was found to be associated with longevity [22174011]. | Human |
| RIMBP2 | RIMS binding protein 2 | RIMBP2 was found to be associated with longevity [22174011]. | Human |
| TUBB4B | tubulin, beta 2C | TUBB4B was found to be associated with longevity [22174011]. | Human |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | XRCC4 was found to be associated with longevity [16518718]. | Human |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | XRCC3 was found to be associated with longevity [16518718]. | Human |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | XRCC1 was found to be associated with longevity [16518718]. | Human |
| SIRT1 | sirtuin 1 | SIRT1 was found to be associated with longevity [21972126; 16257164; 16257164; 16257164; 16257164; 16257164; 21972126; 20633545]. SIRT1 was not found to be associated with longevity [16257164; 18765803].SIRT1 was found to be associated with longevity [23505545]. SIRT1 was found to be associated with longevity [23450480]. SIRT1 was not found to be associated with longevity [23450480]. | Human |
| IL6 | interleukin 6 (interferon, beta 2) | The production of IL-6 is genetically controlled and age- and gender-dependent. IL-6 production bt aPBMC increases with age in C+ but not in C-subjects. [11772517]. | Human |
| TNF | tumor necrosis factor | The frequency of the -308 polymorphism in the TNF gene was analyzed in 71 healthy elders, aged 80 to 96 years (mean 86.2 years). The control samples were obtained from 99 young (from 21 - 54 years; mean 35.2 years) healthy individuals unrelated to elders were studied, age ranged from 80 to 96 years (mean 86.2 years). The TNF2 allele was increased in the elder group when compared to young controls [16269080].TNF was found to be associated with longevity [20518833]. TNF was found to be associated with longevity [18511747]. TNF was found to be associated with longevity [12714268]. TNF was found to be associated with longevity [12714268]. TNF was found to be associated with longevity [12676903]. TNF was found to be associated with longevity [11640949]. TNF was found to be associated with longevity [21299522]. TNF was found to be associated with longevity [21299522]. TNF was not found to be associated with longevity [12676903]. TNF was found to be associated with longevity [16269080]. TNF was not found to be associated with longevity [11640949]. | Human |
| TH | tyrosine hydroxylase | Polymorphyc repeats in intron 1 (Short and Long alleles) of the TH gene were examined in 196 centenarians (143 females and 53 males) and 358 controls (196 females and 162 male; 10-85 years old). A significant loss of LL homozygous genotypes was found at the THO locus in male but not in female centenarians with respect to matched controls [9887369].TH was found to be associated with longevity [12297342]. TH was found to be associated with longevity [21407269]. TH was found to be associated with longevity [19367319]. TH was not found to be associated with longevity [19367319]. TH was found to be associated with longevity [11053670]. TH was found to be associated with longevity [17989723]. | Human |
| TGFB1 | transforming growth factor, beta 1 | 4 SNPs (-800 G/A, -509 C/T, +869 T/C and +915 G/C) in the TGFB1 gene were analysed in 419 subjects from Northern and Central Italy, including 172 centenarians and 247 younger controls. Significant differences were found at the +915 site as far as the C allele and GC genotype were concerned, both of them being lower in centenarians than in young controls, but none of the other tested genetic variants was significantly different between centenarians and controls. Moreover, a particular haplotype combination (G -800/C -509/C 869/C 915) was notably lower in centenarians than in younger individuals [15569360].TGFB1 was found to be associated with longevity [21299522]. TGFB1 was found to be associated with longevity [21299522]. TGFB1 was found to be associated with longevity [15569360]. | Human |
