Denigma: Factor

MIR1

Symbol: MIR1
Entrez gene ID: 853540
Ensembl gene ID: YJR077C
Species: Yeast (Taxid: 4932)

Functional description:
Mir1p; Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated [Source:SGD;Acc:S000003838] [Ensembl]

Observation:

Deletion of MIR1 increases replicative lifespan by 25% in the alpha strain [18340043] and mean chronological lifespan by 43 - 100% (43, 49, 59, 73, 69, 100) in diploid cells [21447998].

Assays: Replicative Lifespan Chronological Lifespan
Mean: +25 to +100

Classification:

Positive Gerontogene

Type:

Gene

References:

18340043: Quantitative evidence for conserved longevity pathways between divergent eukaryotic species.

21447998: A genomic analysis of chronological longevity factors in budding yeast.

Aging Relevance Analysis/Source:

GenAge