LIN1

Symbol: LIN1
Name: LINk
Alias: SNU40
Entrez gene ID: 856561
Ensembl gene ID: YHR156C
Species: Yeast (Taxid: 4932)

Functional description:
Lin1p; Non-essential component of U5 snRNP; nuclear protein; physically interacts with Irr1p of cohesin complex; may link together proteins involved in chromosome segregation, mRNA splicing and DNA replication [Source:SGD;Acc:S000001199] [Ensembl]

Observation:

Deletion of LIN1 increases replicative lifespan [16293764]. LIN1 deletion increases replicative lifespan by 40% in the alpha strain [19030232].



Interventions:
  • LIN1 deletion +40%

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • LIN1 (4932)
  • KLLA0C02629g (28985)
  • AGOS_AFR655C (33169)



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