Denigma

ccr-4

Symbol: ccr-4
Name: CCR (yeast CCR4/NOT complex component) homolog 4
Entrez gene ID: 178184
Ensembl gene ID: ZC518.3
Species: Worm (Taxid: 6239)

Functional description:
Protein CCR-4; CCR (yeast CCR4/NOT complex component) homolog family member (ccr-4) [Source:RefSeq peptide;Acc:NP_001023607] [Ensembl]

Observation:

RNA interference of ccr-4 decreases median lifespan by 33% in wild type animals, 37% in a daf-2 background and 44% in daf-2/daf-16 double mutants [18006689].



Interventions:
  • ccr-4 RNAi -33%

    • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • CNOT6 (9606)
  • CNOT6 (9598)
  • CNOT6 (9615)
  • CNOT6 (9913)
  • Cnot6 (10090)
  • Cnot6 (10116)
  • CNOT6 (9031)
  • cnot6 (7955)
  • twin (7227)
  • AgaP_AGAP004405 (7165)
  • ccr-4 (6239)



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