cco-2

Symbol: cco-2
Name: Cytochrome C Oxidase 2
Entrez gene ID: 176707
Ensembl gene ID: Y37D8A.14
Species: Worm (Taxid: 6239)

Functional description:
This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. [UniProt]

Observation:

RNA interference of cco-2 results in a 53-57% increase in mean lifespan [16103914].



Interventions:
  • cco-2 RNAi +45 to +57%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • COX5A (9606)
  • COX5A (9598)
  • LOC478370 (9615)
  • LOC610768 (9615)
  • COX5A (9913)
  • Cox5a (10090)
  • Cox5a (10116)
  • cox5aa (7955)
  • cox5ab (7955)
  • CoVa (7227)
  • AgaP_AGAP011159 (7165)
  • cco-2 (6239)



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