IDP1

Symbol: IDP1
Name: Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes
Entrez gene ID: 851493
Species: Yeast (Taxid: 4932)

Functional description:
Idp1p; Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes [Source:SGD;Acc:S000002224] [Ensembl]

Observation:

Replicative lifespan increased by 15% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • IDH1 (9606)
  • IDH1 (9598)
  • IDH1 (9615)
  • IDH1 (9913)
  • Idh1 (10090)
  • Idh1 (10116)
  • IDH1 (9031)
  • idh1 (7955)
  • Idh (7227)
  • AgaP_AGAP006660 (7165)
  • F59B8.2 (6239)
  • idp1 (4896)
  • IDP1 (4932)
  • KLLA0B03355g (28985)
  • AGOS_AER061C (33169)
  • GeneID:2683014 (148305)
  • NCU03857 (5141)
  • AT1G65930 (3702)
  • Os01g0654500 (4530)
  • Os05g0573200 (4530)



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