GIN4

Symbol: GIN4
Name: Growth Inhibitory 4
Entrez gene ID: 852119
Ensembl gene ID: YDR507C
Species: Yeast (Taxid: 4932)

Functional description:
Gin4p; Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Kcc4p and Hsl1p [Source:SGD;Acc:S000002915] [Ensembl]

Observation:

Deletion of GIN4 decreases replicative lifespan by 35% in the alpha strain [18340043; 19030232].



Interventions:
  • GIN4 deletion -35%

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • GIN4 (4932)
  • KLLA0C01650g (28985)
  • AGOS_AFR696C (33169)



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