ELP4

Symbol: ELP4
Name: Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity
Entrez gene ID: 856002
Species: Yeast (Taxid: 4932)

Functional description:
Elp4p; Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity [Source:SGD;Acc:S000006022] [Ensembl]; Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity [SGD]

Observation:

Replicative lifespan increased by 10-30% in both alpha and a strains



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SPCC11E10.06c (4896)
  • ELP4 (4932)
  • KLLA0E24355g (28985)
  • GeneID:2682966 (148305)
  • NCU08031 (5141)



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