Symbol: car Name: carnation Entrez gene ID: 32947 Ensembl gene ID: FBgn0000257 Species: Fly (Taxid: 7227) Functional description: Vps 33, sec1 protein; Required for the biogenesis of eye pigment granules. Plays a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. [UniProt] Observation: Loss-of-function mutation in car results in reduction of mean lifespan by 34 - 63% and maximum lifespan by 28 - 29% [17435236]. Interventions: Assays: Organismal Lifespan Mean: -34 to -53 Maximum: -28 to -29 Classification: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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