Denigma

CRC1

Symbol: CRC1
Name: CaRnitine Carrier 1
Entrez gene ID: 854267
Ensembl gene ID: YOR100C
Species: Yeast (Taxid: 4932)

Functional description:
Crc1p; Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation [Source:SGD;Acc:S000005626] [Ensembl]

Observation:

Deletion of CRC1 increases replicative lifespan [16293764]. CRC1 deletion increases replicative lifespan by 25% in the alpha strain [19030232]



Interventions:
  • CRC1 deletion +25%

    • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • SLC25A20 (9606)
  • SLC25A20 (9598)
  • SLC25A20 (9913)
  • Slc25a20 (10090)
  • Slc25a20 (10116)
  • slc25a20 (7955)
  • colt (7227)
  • AgaP_AGAP006104 (7165)
  • dif-1 (6239)
  • CRC1 (4932)
  • KLLA0C13431g (28985)
  • AGOS_ADL264C (33169)
  • GeneID:2682059 (148305)
  • NCU07263 (5141)
  • BOU (3702)
  • Os10g0573800 (4530)
  • Os10g0573700 (4530)



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