CDH1

Symbol: CDH1
Name: Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including CDC20, ASE1, CIN8 and FIN1
Entrez gene ID: 852881
Species: Yeast (Taxid: 4932)

Functional description:
Cdh1p; Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p [Source:SGD;Acc:S000002971] [Ensembl]

Observation:

Replicative lifespan decreased by 45% in the alpha strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • FZR1 (9606)
  • FZR1 (9615)
  • FZR1 (9913)
  • FZR1 (9913)
  • Fzr1 (10090)
  • Fzr1 (10116)
  • FZR1 (9031)
  • fzr1 (7955)
  • rap (7227)
  • AgaP_AGAP002114 (7165)
  • fzr-1 (6239)
  • srw1 (4896)
  • CDH1 (4932)
  • KLLA0A08822g (28985)
  • AGOS_AFL007C (33169)
  • NCU01269 (5141)
  • FZR2 (3702)
  • CCS52A2 (3702)
  • Os03g0123300 (4530)



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