ATG15

Symbol: ATG15
Name: AuTophaGy related 15
Alias: AUT5; CVT17
Entrez gene ID: 850432
Ensembl gene ID: YCR068W
Species: Yeast (Taxid: 4932)

Functional description:
Atg15p; Lipase required for intravacuolar lysis of autophagic bodies and Cvt bodies; targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway [Source:SGD;Acc:S000000664] [Ensembl]

Observation:

Deletion of ATG15 does not affect the lifespan significantly on AL, while DR shortens replicative lifespan of ATG15 deletion mutant by 28% [18690010].



Interventions:
  • ATG15 deletion

  • Assays: Replicative Lifespan

    Classification:
  • DR-Essential


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • atg15 (4896)
  • ATG15 (4932)
  • KLLA0C08679g (28985)
  • AGOS_AAR046C (33169)
  • NCU06436 (5141)

  • Orthologs
  • atg15 (4896)
  • atg15 (4896)



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