ALG12

Symbol: ALG12
Name: Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation
Entrez gene ID: 855764
Species: Yeast (Taxid: 4932)

Functional description:
Alg12p; Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation [Source:SGD;Acc:S000005313] [Ensembl]

Observation:

Replicative lifespan increased by 25% in the alpha strain and 25% in the a strain



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • alg12 (4896)
  • ALG12 (4932)
  • KLLA0C08591g (28985)
  • AGOS_AAR043C (33169)
  • GeneID:2680879 (148305)
  • NCU07472 (5141)



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