AGC1

Symbol: AGC1
Name: Aspartate-Glutamate Carrier
Entrez gene ID: 856132
Ensembl gene ID: YPR021C
Species: Yeast (Taxid: 4932)

Functional description:
Agc1p; Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis [Source:SGD;Acc:S000006225] [Ensembl]

Observation:

Deletion of AGC1 increases replicative lifespan by 30% in the alpha strain [18340043] and increases mean chronological lifespan by 7 - 28% [21447998].



Assays:
Mean: +7-30

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • AGC1 (4932)
  • KLLA0E13443g (28985)
  • AGOS_ADL049W (33169)

  • Note: It also decreased mean chronological lifespan by 29% in one experiment.

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