pas-6

Symbol: pas-6
Entrez gene ID: 178943
Ensembl gene ID: CD4.6
Species: Worm (Taxid: 6239)

Functional description:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). [UniProt]

Observation:

RNAi decreased lifespan of WT, daf-2 and glp-1 mutant.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PSMA1 (9606)
  • PSMA1 (9598)
  • PSMA1 (9615)
  • PSMA1 (9913)
  • Psma1 (10090)
  • Psma1 (10116)
  • PSMA1 (9031)
  • zgc:92726 (7955)
  • Pros35 (7227)
  • AgaP_AGAP010253 (7165)
  • pas-6 (6239)
  • SPAC6G10.04c (4896)
  • PRE5 (4932)
  • KLLA0A10153g (28985)
  • AGOS_AGL336W (33169)
  • GeneID:2677261 (148305)
  • NCU06712 (5141)
  • PAF1 (3702)
  • PAF2 (3702)
  • Os02g0133800 (4530)



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