rpt-2

Symbol: rpt-2
Entrez gene ID: 178988
Ensembl gene ID: F29G9.5
Species: Worm (Taxid: 6239)

Functional description:
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). [UniProt]

Observation:

RNAi decreased lifespan of glp-1 mutant, but not of WT or daf-2 mutant.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • PSMC1 (9606)
  • PSMC1 (9598)
  • PSMC1 (9615)
  • PSMC1 (9913)
  • Psmc1 (10090)
  • Psmc1 (10116)
  • PSMC1 (9031)
  • psmc1b (7955)
  • psmc1a (7955)
  • Pros26.4 (7227)
  • AgaP_AGAP003215 (7165)
  • AgaP_AGAP003216 (7165)
  • rpt-2 (6239)
  • rpt2 (4896)
  • RPT2 (4932)
  • KLLA0F14707g (28985)
  • AGOS_AEL011W (33169)
  • GeneID:2676142 (148305)
  • NCU11271 (5141)
  • AT2G20140 (3702)
  • RPT2a (3702)
  • Os07g0691800 (4530)
  • Os03g0298400 (4530)
  • PF10_0081 (5833)



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