Denigma

rpn-10

Symbol: rpn-10
Entrez gene ID: 172977
Ensembl gene ID: B0205.3
Species: Worm (Taxid: 6239)

Functional description:
Non-ATPase Subunit of the 19S proteosomal component ; Protein RPN-10; proteasome Regulatory Particle, Non-ATPase-like family member (rpn-10) [Source:RefSeq peptide;Acc:NP_492809] [Ensembl]; rpn-10 encodes a protein that contains two ubiquitin interaction motifs and is a member of the von Willebrand factor, type A superfamily similar to the mouse 26S proteasome non-ATP regulatory subunit 4. [WormBase]

Observation:

RNAi decreased lifespan of WT, daf-2 and glp-1 mutant.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PSMD4 (9606)
  • PSMD4 (9913)
  • Psmd4 (10090)
  • Psmd4 (10116)
  • psmd4a (7955)
  • Pros54 (7227)
  • AgaP_AGAP005559 (7165)
  • rpn-10 (6239)
  • rpn10 (4896)
  • RPN10 (4932)
  • KLLA0B03916g (28985)
  • AGOS_ABL078C (33169)
  • GeneID:2678171 (148305)
  • NCU02982 (5141)
  • RPN10 (3702)
  • Os03g0243300 (4530)



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