YBR238C

Symbol: YBR238C
Entrez gene ID: 852540
Ensembl gene ID: YBR238C
Species: Yeast (Taxid: 4932)

Functional description:
hypothetical protein; Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span [Source:SGD;Acc:S000000442] [Ensembl]

Observation:

Deletion of YBR238C increases mean replicative lifespan by 25 to 34% in the alpha and a strains [16293764; 19030232].



Interventions:
  • YBR238C deletion +25 to +34%

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • YBR238C (4932)
  • KLLA0F10461g (28985)
  • AGOS_AFL029W (33169)



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