C33A12.1

Symbol: C33A12.1
Entrez gene ID: 177786
Ensembl gene ID: C33A12.1
Species: Worm (Taxid: 6239)

Functional description:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). [UniProt]

Observation:

RNA interference of C33A12.1 increase mean lifespan by 40% [17608836].



Interventions:
  • C33A12.1 RNAi +40%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • NDUFA5 (9606)
  • NDUFA5 (9598)
  • NDUFA5 (9615)
  • NDUFA5 (9913)
  • Ndufa5 (10090)
  • Ndufa5 (10116)
  • NDUFA5 (9031)
  • zgc:114172 (7955)
  • CG6463 (7227)
  • AgaP_AGAP005621 (7165)
  • C33A12.1 (6239)



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