vit-2

Symbol: vit-2
Name: VITellogenin structural genes (yolk protein genes)
Alias: vitellogenin
Entrez gene ID: 180781
Ensembl gene ID: C42D8.2
Species: Worm (Taxid: 6239)

Functional description:
The vit-2 gene encodes the vitellogenin homolog YP170; cholesterol transport; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development (Potential). [UniProt]

Observation:

vit-2 RNA interference extends mean lifespan by 21-24%. vit-2 is differentially transcribed in daf-16 and daf-2 RNAi animals [12845331].

vit-2 functions in germ-line development by regulating the abundance of native versus oxidized LDL-like lipoproteins [11408580].



Interventions:
  • vit-2 RNAi +21 to +24%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • vit-6 (6239)
  • vit-5 (6239)
  • vit-4 (6239)
  • vit-3 (6239)
  • vit-2 (6239)
  • vit-1 (6239)



  • Edit \ Update (Admin) | Delete

    Comment on This Data Unit