unc-13

Symbol: unc-13
Name: UNCoordinated
Entrez gene ID: 172497
Ensembl gene ID: ZK524.2
Species: Worm (Taxid: 6239)

Functional description:
May form part of a signal transduction pathway, transducing the signal from diacylglycerol to effector functions. One such function could be the release of neurotransmitter from neurons. [UniProt]

Observation:

Mutation in unc-13 results in a 150% life-extension in males, but has no effect on hermaphrodite lifespan [10747056].



Interventions:
  • unc-13 mutation +150%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • UNC13B (9598)
  • unc-13 (6239)



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