Symbol: vps-22 Name: related to yeast Vacuolar Protein Sorting factor 22 Entrez gene ID: 175672 Ensembl gene ID: C27F2.5 Species: Worm (Taxid: 6239) Functional description: Protein VPS-22; Protein VPS-22 [Source:UniProtKB/TrEMBL;Acc:Q18258] [Ensembl]; C27F2.5 encodes the C. elegans ortholog of the conserved vacuolar protein sorting protein EAP30/SNF8/VPS22; by homology, the product of C27F2.5 is predicted to be a component of an ESCRT-II complex (Endosomal Sorting Complex Required for Transport) that functions in endosomal transport. [WormBase] Observation: RNA interference of vps-22 decreases median lifespan by 43% in wild type animals, 33% in a daf-2 background and 9% in daf-2/daf-16 double mutants [18006689]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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