tax-4

Symbol: tax-4
Name: abnormal CHEmotaxis
Entrez gene ID: 176297
Ensembl gene ID: ZC84.2
Species: Worm (Taxid: 6239)

Functional description:
Required for normal thermosensation and chemosensation sensory behavior. [UniProt]

Observation:

Recessive loss-of-function allele in tax-4 can increase lifespan by up to 100%. Lifespan extension by tax-4 mutation is suppressed by daf-16 and gonad ablation [10617200].

tax-4 mutants are thermotaxis and chemotaxis defective [8893027; 8348618]. Mutants are slighlty dauer constitutive and form dauers at 27 degree Celsius [9486798].



Interventions:
  • tax-4 mutation +100%

  • Assays: Organismal Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • CNGA1 (9606)
  • CNGA1 (9598)
  • CNGA1 (9615)
  • CNGA1 (9913)
  • Cnga1 (10090)
  • Cnga1 (10116)
  • CNGA1 (9031)
  • LOC100333067 (7955)
  • LOC572249 (7955)
  • tax-4 (6239)



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