him-6

Symbol: him-6
Alias: blm-1
Entrez gene ID: 178201
Ensembl gene ID: T04A11.6
Species: Worm (Taxid: 6239)

Functional description:
Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). [UniProt]

Observation:

him-6 mutants have a low brood size, a shortened lifespan, and an increased amount of germ-line apoptosis [16181657].



Interventions:
  • him-6 RNAi

  • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • mus309 (7227)
  • AgaP_AGAP002967 (7165)
  • him-6 (6239)



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