Denigma

syd-2

Symbol: syd-2
Name: SYnapse Defective
Entrez gene ID: 181255
Ensembl gene ID: F59F5.6
Species: Worm (Taxid: 6239)

Functional description:
Required cell autonomously in neurons for differentiation of presynaptic active zones; May play a role in regulating the structure of the neuronal region, called the active zone, from which synaptic vesicles send neurotransmitter signals across the synapse. [UniProt]

Observation:

Mutation reduced maximum lifespan 40%.



Assays:

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • PPFIA1 (9606)
  • PPFIA1 (9598)
  • PPFIA1 (9615)
  • PPFIA1 (9913)
  • Ppfia1 (10090)
  • Ppfia1 (10116)
  • PPFIA1 (9031)
  • zgc:171298 (7955)
  • Liprin-alpha (7227)
  • AgaP_AGAP001469 (7165)
  • syd-2 (6239)



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