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Symbol: sug Name: sugarbabe Entrez gene ID: 39314 Ensembl gene ID: FBgn0036191 Species: Fly (Taxid: 7227) Functional description: Sugar baby is related to maltose permease form Bacillus starothermophilus; CG7334 gene product from transcript CG7334-RE; Sug [Source:FlyBase gene name;Acc:FBgn0036191] [Ensembl]; The gene Sug is referred to in FlyBase by the symbol Dmel\Sug (CG7334, FBgn0036191). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: determination of adult lifespan. 13 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Major facilitator superfamily; Major facilitator superfamily domain; Major facilitator superfamily domain, general substrate transporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed in adult female stages. [FlyBase] Observation: Overexpression of sug (from a doxycycline-inducible promoter) results in a 5-9% increase in mean lifespan [12620118]. Interventions: Assays: Organismal Lifespan Mean: +5 to +9 Classification: Type: References: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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